Weston Brain Institute - Big Ideas

Neurodegenerative diseases of aging are among the least understood and most undertreated diseases today. If ignored, the social and economic costs of managing these diseases will continue to rise. Meeting these challenges requires pioneering approaches to accelerating treatments.

Based on success of previous programs, the Institute is expanding our support to new formats while maintaining the same mandate of accelerating the developments of therapeutics for neurodegenerative diseases of aging through translational research.

The Institute is considering supporting a large-scale, pivotal project to significantly advance research in our field. With this call, we are seeking to identify highly impactful ideas for consideration. Of particular interest are ideas that will establish Canada as the world leader in a particular area.

Please refer to the Program Call and Request for Applications (RFA) document for more information.

Goal: To support a large-scale, pivotal project that will significantly and sustainably advance research in the field of translational research on neurodegenerative diseases of aging.

Applicant Eligibility: Eligible Principal Applicants must be working in Canada at least 30% of the time at or above the level of Assistant Professor or equivalent, and be affiliated with a Canada Revenue Agency-qualified donee institution located in Canada. Co-Applicants/Collaborators must be at the post-doctoral level or above and can be working outside Canada.

Applicants may appear in any role on any number of projects.

Project Eligibility: 

Submissions must:

  • Have a significant and sustained impact on translational research to accelerate the development of therapeutics for neurodegenerative diseases of aging.
  • Be led by Canadian-based researchers.

Projects must have a significant and sustained impact on accelerating translational research on the development of therapeutics for neurodegenerative diseases of aging.  Other project aspects are flexible, e.g.:

  • Submissions do not need to be fully developed at this stage
  • Submission do not need to be hypothesis based research questions
  • Participants can range from individual investigators/centres to international consortia or collaborative projects

High potential projects may also (but not necessarily):

  • Be “flagship” projects for Canada,
  • Provide a platform for Canadian researchers to be recognized internationally
  • Bring international resources, people or organizations into Canadian-led work
  • Bring additional funding or other resources if/as needed

Please refer to What We Fund for Institute definitions of neurodegenerative diseases of aging, translational research, therapeutic, and tool, and more. The Institute welcomes additional inquiries about this program. Please contact Alexandra Stewart with questions, including whether a potential idea is in scope.

Agency Name: 
Weston Brain Institute
Contact Name: 
Penny D'Agnone
Grant Amount: 
Funding: From $5,000,000 to $20,000,000.
Grant Location: 
Grant Type: 
Grant Area: 
Grant Eligibility: