Browsing Faculty Research and Publications by Author "Kovalchuk, Olga"

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  • Yao, Youli; Robinson, Alexandra M.; Zucchi, Fabiola C. R.; Robbins, Jerrah C.; Babenko, Olena M.; Kovalchuk, Olga; Kovalchuk, Igor; Olson, David M.; Metz, Gerlinde A. S. (BioMed CentralArts and ScienceDepartment of Biological SciencesUniversity of LethbridgeUniversity of Alberta, 2014)
    Abstract Background: Chronic stress is considered to be one of many causes of human preterm birth (PTB), but no direct evidence has yet been provided. Here we show in rats that stress across generations has downstream ...
  • Krishnan, Preethi; Ghosh, Sunita; Wang, Bo; Heyns, Mieke; Li, Dongping; Mackey, John R.; Kovalchuk, Olga; Damaraju, Sambasivarao (Nature Publishing GroupArts and ScienceDepartment of Biological SciencesUniversity of AlbertaCross Cancer InstituteUniversity of Lethbridge, 2016)
    Transfer RNAs (tRNAs, key molecules in protein synthesis) have not been investigated as potential prognostic markers in breast cancer (BC), despite early findings of their dysregulation and diagnostic potential. We aim ...
  • Kovalchuk, Igor; Walz, Paul; Thomas, James; Kovalchuk, Olga (Public Library of ScienceArts and ScienceDepartment of Biological SciencesUniversity of Lethbridge, 2013)
    Bacterial infection has been linked to carcinogenesis, however, there is lack of knowledge of molecular mechanisms that associate infection with the development of cancer. We analyzed possible effects of the consumption ...
  • Zucchi, Fabiola C. R.; Yao, Youli; Ilnytskyy, Yaroslav; Robbins, Jerrah C.; Soltanpour, Nasrin; Kovalchuk, Igor; Kovalchuk, Olga; Metz, Gerlinde A. S. (Public Library of ScienceArts and ScienceDepartment of Biological SciencesDepartment of NeuroscienceUniversity of LethbridgeUniversity of Mato Grosso State, 2014)
    Prenatal stress (PS) represents a critical variable affecting lifetime health trajectories, metabolic and vascular functions. Beneficial experiences may attenuate the effects of PS and its programming of health outcomes ...
  • Zucchi, Fabiola C. R.; Yao, Youli; Ward, Isaac D.; Ilnytskyy, Yaroslav; Olson, David M.; Benzies, Karen; Kovalchuk, Igor; Kovalchuk, Olga; Metz, Gerlinde A. S. (Public Library of ScienceArts and ScienceDepartment of NeuroscienceDepartment of Biological SciencesUniversity of LethbridgeUniversity of Mato Grosso StateUniversity of AlbertaUniversity of Calgary, 2013)
    The gestational state is a period of particular vulnerability to diseases that affect maternal and fetal health. Stress during gestation may represent a powerful influence on maternal mental health and offspring brain ...
  • Krishnan, Preethi; Ghosh, Sunita; Wang, Bo; Li, Dongping; Narasimhan, Ashok; Berendt, Richard; Graham, Kathryn; Mackey, John R.; Kovalchuk, Olga; Damaraju, Sambasivarao (BioMed CentralArts and ScienceDepartment of Biological SciencesUniversity of AlbertaCross Cancer InstituteUniversity of Lethbridge, 2015)
    Background: Prognostication of Breast Cancer (BC) relies largely on traditional clinical factors and biomarkers such as hormone or growth factor receptors. Due to their suboptimal specificities, it is challenging to ...
  • Kovalchuk, Anna; Mychasiuk, Richelle; Muhammad, Arif; Hossain, Shakhawat; Ilnytskyy, Yaroslav; Ghose, Abhijit; Kirkby, Charles; Ghasroddashti, Esmaeel; Kolb, Bryan; Kovalchuk, Olga (Frontiers MediaArts and ScienceDepartment of NeuroscienceDepartment of Biological SciencesUniversity of LethbridgeAlberta Epigenetics NetworkUniversity of CalgaryAlberta Health ServicesCanadian Institute for Advanced Research, 2016)
    Irradiated cells can signal damage and distress to both close and distant neighbors that have not been directly exposed to the radiation (naïve bystanders). While studies have shown that such bystander effects occur in the ...
  • Kovalchuk, Igor; Kovalchuk, Olga (M D P I A GArts and ScienceDepartment of Biological SciencesUniversity of Lethbridge, 2008)
    Rapid technological development is inevitably associated with many environmental problems which primarily include pollution of soil, water and air. In many cases, the presence of contamination is difficult to assess. It ...

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