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Browsing Faculty Research and Publications by Title

Browsing Faculty Research and Publications by Title

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  • Babenko, Olena; Golubov, Andrey; Ilnytskyy, Yaroslav; Kovalchuk, Igor; Metz, Gerlinde A. S. (Public Library of ScienceArts and ScienceDepartment of Biological SciencesCanadian Centre for Behavioural NeuroscienceUniversity of LethbridgeUniversity of Calgary, 2012)
    Stress represents a critical influence on motor system function and has been shown to impair movement performance. We hypothesized that stress-induced motor impairments are due to brain-specific changes in miRNA and ...
  • Gonzalez, Claudia L. R.; Mills, Kelly J.; Genee, Inge; Li, Fangfang; Piquette-Tomei, Noëlla A.; Rosen, Nicole; Gibb, Robbin L. (FrontiersArts and ScienceEducationDepartment of KinesiologyDepartment of Modern LanguagesDepartment of PsychologyDepartment of NeuroscienceUniversity of Lethbridge, 2014)
    Executive Function (EF) refers to important socio-emotional and cognitive skills that are known to be highly correlated with both academic and life success. EF is a blanket term that is considered to include self-regulation, ...
  • Akaho, Shotaro; Higuchi, Sho; Iwasaki, Taishi; Hino, Hideitsu; Tatsuno, Masami; Murata, Noboru (IOP Publishing, 2016)
    We propose a method to extract connectivity between neurons for extracellularly recorded multiple spike trains. The method removes pseudo-correlation caused by propagation of information along an indirect pathway, and ...
  • Kolb, Bryan; Muhammad, Arif (Frontiers MediaArts and ScienceDepartment of NeuroscienceUniversity of Lethbridge, 2014)
    A fundamental property of the brain is its capacity to change with a wide variety of experiences, including injury. Although there are spontaneous reparative changes following injury, these changes are rarely sufficient ...
  • Lansink, Carien S.; Goltstein, Pieter M.; Lankelma, Jan V.; McNaughton, Bruce L.; Pennartz, Cyriel M. A. (Public Library of ScienceArts and ScienceDepartment of NeuroscienceUniversity of AmsterdamUniversity of Lethbridge, 2009)
    Associating spatial locations with rewards is fundamental to survival in natural environments and requires the integrity of the hippocampus and ventral striatum. In joint multineuron recordings from these areas, ...
  • Proft, Juliane; Faraji, Jamshid; Robbins, Jerrah C.; Zucchi, Fabiola C. R.; Zhao, Xiaoxi; Metz, Gerlinde A. S.; Braun, Janice E. A. (Public Library of ScienceArts and ScienceDepartment of NeuroscienceUniversity of CalgaryUniversity of LethbridgeGolestan University of Medical Sciences, 2011)
    Parkinson’s disease (PD) is a common neurodegenerative disease characterized by the loss of dopaminergic neurons in the substantia nigra and the aggregation of a-synuclein into Lewy bodies. Existing therapies address motor ...
  • Hehar, Harleen; Yeates, Keith; Kolb, Bryan; Esser, Michael J.; Mychasiuk, Richelle (Public Library of ScienceArts and ScienceDepartment of NeuroscienceUniversity of CalgaryUniversity of Lethbridge, 2015)
    Impulsivity and poor executive control have been implicated in the pathogenesis of many developmental and neuropsychiatric disorders. Similarly, concussions/mild traumatic brain injuries (mTBI) have been associated with ...
  • Nie, Yimin; Fellous, Jean-Marc; Tatsuno, Masami (Frontiers Research FoundationArts and ScienceDepartment of NeuroscienceUniversity of LethbridgeUniversity of Arizona, 2014)
    The characterization of functional network structures among multiple neurons is essential to understanding neural information processing .Information geometry (IG) ,a theory developed for investigating a space of probability ...
  • Wylie, Douglas R.; Gutierrez-Ibanez, Cristian I.; Iwaniuk, Andrew N. (Frontiers MediaArts and ScienceDepartment of NeuroscienceUniversity of AlbertaTechnische Universität MünchenUniversity of Lethbridge, 2015)
    The comparative anatomy of sensory systems has played a major role in developing theories and principles central to evolutionary neuroscience. This includes the central tenet of many comparativestudies, the principle of ...
  • Erickson, Zachary T.; Falkenberg, Erin A.; Metz, Gerlinde A. S. (Public Library of ScienceArts and ScienceDepartment of NeuroscienceUniversity of Lethbridge, 2014)
    The consumption of artificial food dye (AFD) during childhood and adolescence has been linked to behavioural changes, such as hyperactivity. It is possible that the vulnerability to AFDs is modified by prenatal stress. ...
  • Zucchi, Fabiola C. R.; Yao, Youli; Ilnytskyy, Yaroslav; Robbins, Jerrah C.; Soltanpour, Nasrin; Kovalchuk, Igor; Kovalchuk, Olga; Metz, Gerlinde A. S. (Public Library of ScienceArts and ScienceDepartment of Biological SciencesDepartment of NeuroscienceUniversity of LethbridgeUniversity of Mato Grosso State, 2014)
    Prenatal stress (PS) represents a critical variable affecting lifetime health trajectories, metabolic and vascular functions. Beneficial experiences may attenuate the effects of PS and its programming of health outcomes ...
  • Zucchi, Fabiola C. R.; Yao, Youli; Ward, Isaac D.; Ilnytskyy, Yaroslav; Olson, David M.; Benzies, Karen; Kovalchuk, Igor; Kovalchuk, Olga; Metz, Gerlinde A. S. (Public Library of ScienceArts and ScienceDepartment of NeuroscienceDepartment of Biological SciencesUniversity of LethbridgeUniversity of Mato Grosso StateUniversity of AlbertaUniversity of Calgary, 2013)
    The gestational state is a period of particular vulnerability to diseases that affect maternal and fetal health. Stress during gestation may represent a powerful influence on maternal mental health and offspring brain ...
  • Christie, Gregory J.; Cook, Charles M.; Ward, Brian J.; Tata, Matthew S.; Sutherland, Janice; Sutherland, Robert J.; Saucier, Deborah M. (Public Library of ScienceArts and ScienceDepartment of NeuroscienceUniversity of LethbridgeSimon Fraser UniversityUniversity of Ontario Institute of Technology, 2013)
    This study investigated how both sex and individual differences in a mental rotation test (MRT) influence performance on working memory (WM). To identify the neural substrate supporting these differences, brain electrical ...
  • Gutierrez-Ibanez, Cristian I.; Iwaniuk, Andrew N.; Moore, Bret A.; Fernandez-Juricic, Esteban; Corfield, Jeremy R.; Krilow, Justin M.; Kolominsky, Jeffrey; Wylie, Douglas R. (Public Library of ScienceArts and ScienceDepartment of NeuroscienceUniversity of AlbertaUniversity of LethbridgePurdue University, 2014)
    Two main models have been proposed to explain how the relative size of neural structures varies through evolution. In the mosaic evolution model, individual brain structures vary in size independently of each other, whereas ...
  • Holec, Victoria; Pirot, Heather L.; Euston, David R. (Frontiers Research FoundationsArts and ScienceDepartment of NeuroscienceUniversity of Lethbridge, 2014)
    The rat anterior cingulate cortex (ACC) mediates effort-based decision making when the task requires the physical effort of climbing a ramp. Normal rats will readily climb a barrier leading to high reward whereas rats ...
  • Milstein, Jean A.; Elnabawi, Ahmed; Vinish, Monika; Swanson, Thomas; Enos, Jennifer K.; Bailey, Aileen M.; Kolb, Bryan; Frost, Douglas O. (Public Library of ScienceArts and ScienceDepartment of NeuroscienceUniversity of Maryland School of MedicineSt. Mary's College of MarylandUniversity of Lethbridge, 2013)
    Antipsychotic drugs are increasingly used in children and adolescents to treat a variety of psychiatric disorders. However, little is known about the long-term effects of early life antipsychotic drug treatment. Most ...
  • Gibb, Robbin L.; University of Lethbridge. Faculty of Arts and Science (Lethbridge, Alta. : University of Lethbridge, Faculty of Arts and Science, 2004Arts and ScienceDepartment of Neuroscience, 2004)
    Brain damage in the first week of life is behaviorally and anatomically devastating for a rat. I investigated the use of pre- and/or postnatal experience as interventions that might improve the outcomes in rats with ...
  • Kolb, Bryan; Gibb, Robbin L. (Frontiers MediaArts and ScienceDepartment of NeuroscienceUniversity of Lethbridge, 2015)
    We review the plastic changes of the prefrontal cortex of the rat in response to a wide range of experiences including sensory and motor experience, gonadal hormones, psychoactive drugs, learning tasks, stress, social ...
  • Gibb, Robbin L.; Gonzalez, Claudia L. R.; Kolb, Bryan (Frontiers Research FoundationArts and ScienceDepartment of NeuroscienceUniversity of Lethbridge, 2014)
    Birth is a particularly vulnerable time for acquiring brain injury. Unfortunately, very few treatments are available for those affected. Here we explore the effectiveness of prenatal intervention in an animal model of early ...
  • Kovalchuk, Anna; Mychasiuk, Richelle; Muhammad, Arif; Hossain, Shakhawat; Ilnytskyy, Yaroslav; Ghose, Abhijit; Kirkby, Charles; Ghasroddashti, Esmaeel; Kolb, Bryan; Kovalchuk, Olga (Frontiers MediaArts and ScienceDepartment of NeuroscienceDepartment of Biological SciencesUniversity of LethbridgeAlberta Epigenetics NetworkUniversity of CalgaryAlberta Health ServicesCanadian Institute for Advanced Research, 2016)
    Irradiated cells can signal damage and distress to both close and distant neighbors that have not been directly exposed to the radiation (naïve bystanders). While studies have shown that such bystander effects occur in the ...

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