Neuroscience

 

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  • Proft, Juliane; Faraji, Jamshid; Robbins, Jerrah C.; Zucchi, Fabiola C. R.; Zhao, Xiaoxi; Metz, Gerlinde A. S.; Braun, Janice E. A. (Public Library of ScienceArts and ScienceDepartment of NeuroscienceUniversity of CalgaryUniversity of LethbridgeGolestan University of Medical Sciences, 2011)
    Parkinson’s disease (PD) is a common neurodegenerative disease characterized by the loss of dopaminergic neurons in the substantia nigra and the aggregation of a-synuclein into Lewy bodies. Existing therapies address motor ...
  • Metzler, Megan J.; Saucier, Deborah M.; Metz, Gerlinde A. S. (Frontiers Research FoundationArts and ScienceDepartment of NeuroscienceUniversity of LethbridgeUniversity of Ontario Institute of Technology, 2013)
    Aging is associated with deterioration of skilled manual movement. Specifically, aging corresponds with increased reaction time, greater movement duration, segmentation of movement, increased movement variability, and ...
  • Faraji, Jamshid; Soltanpour, Nabiollah; Moeeini, Reza; Roudaki, Shabnam; Soltanpour, Nasrin; Abdollahi, Ali-Akbar; Metz, Gerlinde A. S. (Frontiers Research FoundationArts and ScienceDepartment of NeuroscienceUniversity of LethbridgeGolestan University of Medical SciencesBabol University of Medical SciencesAvicenna Institute of Neuroscience, 2014)
    Silent focal ischemic mini infarcts in the brain are thought to cause no clinically overt symptoms. Some populations of hippocampal cells are particularly sensitive to ischemic events, however, rendering hippocampal ...
  • Kovalchuk, Anna; Mychasiuk, Richelle; Muhammad, Arif; Hossain, Shakhawat; Ilnytskyy, Yaroslav; Ghose, Abhijit; Kirkby, Charles; Ghasroddashti, Esmaeel; Kolb, Bryan; Kovalchuk, Olga (Frontiers MediaArts and ScienceDepartment of NeuroscienceDepartment of Biological SciencesUniversity of LethbridgeAlberta Epigenetics NetworkUniversity of CalgaryAlberta Health ServicesCanadian Institute for Advanced Research, 2016)
    Irradiated cells can signal damage and distress to both close and distant neighbors that have not been directly exposed to the radiation (naïve bystanders). While studies have shown that such bystander effects occur in the ...
  • Kolb, Bryan; Teskey, G. Campbell; Gibb, Robbin L. (Frontiers Research FoundationArts and ScienceDepartment of NeuroscienceUniversity of LethbridgeUniversity of Calgary, 2010)
    An important development in behavioral neuroscience in the past 20 years has been the demonstration that it is possible to stimulate functional recovery after cerebral injury in laboratory animals. Rodent models of ...
  • Milstein, Jean A.; Elnabawi, Ahmed; Vinish, Monika; Swanson, Thomas; Enos, Jennifer K.; Bailey, Aileen M.; Kolb, Bryan; Frost, Douglas O. (Public Library of ScienceArts and ScienceDepartment of NeuroscienceUniversity of Maryland School of MedicineSt. Mary's College of MarylandUniversity of Lethbridge, 2013)
    Antipsychotic drugs are increasingly used in children and adolescents to treat a variety of psychiatric disorders. However, little is known about the long-term effects of early life antipsychotic drug treatment. Most ...
  • Hehar, Harleen; Yeates, Keith; Kolb, Bryan; Esser, Michael J.; Mychasiuk, Richelle (Public Library of ScienceArts and ScienceDepartment of NeuroscienceUniversity of CalgaryUniversity of Lethbridge, 2015)
    Impulsivity and poor executive control have been implicated in the pathogenesis of many developmental and neuropsychiatric disorders. Similarly, concussions/mild traumatic brain injuries (mTBI) have been associated with ...
  • Nie, Yimin; Fellous, Jean-Marc; Tatsuno, Masami (Frontiers Research FoundationArts and ScienceDepartment of NeuroscienceUniversity of LethbridgeUniversity of Arizona, 2014)
    The characterization of functional network structures among multiple neurons is essential to understanding neural information processing .Information geometry (IG) ,a theory developed for investigating a space of probability ...
  • Wylie, Douglas R.; Gutierrez-Ibanez, Cristian I.; Iwaniuk, Andrew N. (Frontiers MediaArts and ScienceDepartment of NeuroscienceUniversity of AlbertaTechnische Universität MünchenUniversity of Lethbridge, 2015)
    The comparative anatomy of sensory systems has played a major role in developing theories and principles central to evolutionary neuroscience. This includes the central tenet of many comparativestudies, the principle of ...
  • Corfield, Jeremy R.; Price, Kasandra; Iwaniuk, Andrew N.; Gutierrez-Ibanez, Cristian I.; Birkhead, Tim R.; Wylie, Douglas R. (Frontiers MediaArts and ScienceDepartment of NeuroscienceUniversity of AlbertaUniversity of LethbridgeTechnische Universität MünchenUniversity of Sheffield, 2015)
    The relative size of olfactory bulbs (OBs) is correlated with olfactory capabilities across vertebrates and is widely used to assess the relative importance of olfaction to a species’ ecology. In birds, variations in the ...
  • Sol, Daniel; Garcia, Nuria; Iwaniuk, Andrew N.; Davis, Katie; Meade, Andrew; Boyle, W. Alice; Szekely, Tamas (Public Library of ScienceArts and ScienceDepartment of NeuroscienceAutonomous University of BarcelonaCentre for Advanced Studies of Blanes-Spanish National Research Council-Spanish National Research CouncilUniversity of LethbridgeUniversity of ReadingUniversity of GlasgowUniversity of Western OntarioUniversity of Bath, 2010)
    Despite important recent progress in our understanding of brain evolution, controversy remains regarding the evolutionary forces that have driven its enormous diversification in size. Here, we report that in passerine ...
  • Walsh, Stig A.; Iwaniuk, Andrew N.; Knoll, Monja A.; Bourdon, Estelle; Barrett, Paul M.; Milner, Angela C.; Nudds, Robert L.; Abel, Richard L.; Sterpaio, Patricia Dello (Public Library of ScienceArts and ScienceDepartment of NeuroscienceNational Museums of ScotlandUniversity of LethbridgeUniversity of the West of ScotlandNatural History Museum (London, England)University of ManchesterImperial College, LondonUniversity of Abertay Dundee, 2013)
    Extinct animal behavior has often been inferred from qualitative assessments of relative brain region size in fossil endocranial casts. For instance, flight capability in pterosaurs and early birds has been inferred from ...
  • Gutierrez-Ibanez, Cristian I.; Iwaniuk, Andrew N.; Moore, Bret A.; Fernandez-Juricic, Esteban; Corfield, Jeremy R.; Krilow, Justin M.; Kolominsky, Jeffrey; Wylie, Douglas R. (Public Library of ScienceArts and ScienceDepartment of NeuroscienceUniversity of AlbertaUniversity of LethbridgePurdue University, 2014)
    Two main models have been proposed to explain how the relative size of neural structures varies through evolution. In the mosaic evolution model, individual brain structures vary in size independently of each other, whereas ...
  • Gutierrez-Ibanez, Cristian I.; Iwaniuk, Andrew N.; Lisney, Thomas J.; Faunes, Macarena; Marin, Gonzalo J.; Wylie, Douglas R. (Public Library of ScienceArts and ScienceDepartment of NeuroscienceUniversity of AlbertaUniversity of LethbridgeUniversidad de ChileUniversidad Finis Terrae, 2013)
    In birds, there is a retinofugal projection from the brain to the retina originating from the isthmo optic nucleus (ION) in the midbrain. Despite a large number of anatomical, physiological and histochemical studies, the ...
  • Cunningham, Susan J.; Corfield, Jeremy R.; Iwaniuk, Andrew N.; Castro, Isabel; Alley, Maurice R.; Birkhead, Tim R.; Parsons, Stuart (Public Library of ScienceArts and ScienceDepartment of NeuroscienceUniversity of Cape TownMassey UniversityUniversity of LethbridgeUniversity of SheffieldUniversity of Auckland, 2013)
    Three families of probe-foraging birds, Scolopacidae (sandpipers and snipes), Apterygidae (kiwi), and Threskiornithidae (ibises, including spoonbills) have independently evolved long, narrow bills containing clusters ...
  • Corfield, Jeremy R.; Gsell, Anna C.; Brunton, Dianne; Heesy, Christopher P.; Hall, Margaret I.; Acosta, Monica L.; Iwaniuk, Andrew N. (Public Library of ScienceArts and ScienceDepartment of NeuroscienceUniversity of LethbridgeMassey UniversityMidwestern UniversityUniversity of Auckland, 2011)
    The shift from a diurnal to nocturnal lifestyle in vertebrates is generally associated with either enhanced visual sensitivity or a decreased reliance on vision. Within birds, most studies have focused on differences in ...
  • Aspden, Joel W.; Armstrong, Carol L.; Gutierrez-Ibanez, Cristian I.; Hawkes, Richard; Iwaniuk, Andrew N.; Kohl, Tobias; Graham, David J.; Wylie, Douglas R. (Public Library of ScienceArts and ScienceDepartment of NeuroscienceUniversity of AlbertaMount Royal UniversityTechnische Universität MünchenUniversity of CalgaryUniversity of Lethbridge, 2015)
    Aldolase C, also known as Zebrin II (ZII), is a glycolytic enzyme that is expressed in cerebellar Purkinje cells of the vertebrate cerebellum. In both mammals and birds, ZII is expressed heterogeneously, such that there ...
  • Gonzalez, Claudia L. R.; Li, Fangfang; Mills, Kelly J.; Rosen, Nicole; Gibb, Robbin L. (Frontiers MediaArts and ScienceDepartment of Kinesiology and Physical EducationDepartment of PsychologyDepartment of NeuroscienceUniversity of LethbridgeUniversity of Manitoba, 2014)
    Degree of lateralization for grasping predicts the maturity of the language production system in young, typically-developing children. In this report we provide compelling evidence for the relationship between right hand ...
  • Zucchi, Fabiola C. R.; Yao, Youli; Ward, Isaac D.; Ilnytskyy, Yaroslav; Olson, David M.; Benzies, Karen; Kovalchuk, Igor; Kovalchuk, Olga; Metz, Gerlinde A. S. (Public Library of ScienceArts and ScienceDepartment of NeuroscienceDepartment of Biological SciencesUniversity of LethbridgeUniversity of Mato Grosso StateUniversity of AlbertaUniversity of Calgary, 2013)
    The gestational state is a period of particular vulnerability to diseases that affect maternal and fetal health. Stress during gestation may represent a powerful influence on maternal mental health and offspring brain ...
  • Babenko, Olena; Golubov, Andrey; Ilnytskyy, Yaroslav; Kovalchuk, Igor; Metz, Gerlinde A. S. (Public Library of ScienceArts and ScienceDepartment of Biological SciencesCanadian Centre for Behavioural NeuroscienceUniversity of LethbridgeUniversity of Calgary, 2012)
    Stress represents a critical influence on motor system function and has been shown to impair movement performance. We hypothesized that stress-induced motor impairments are due to brain-specific changes in miRNA and ...

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