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The effect of playful experiences on the plasticity and metaplasticity of the brain

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dc.contributor.advisor Pellis, Sergio
dc.contributor.advisor Kolb, Bryan
dc.contributor.author Himmler, Brett T
dc.contributor.author University of Lethbridge. Faculty of Arts and Science
dc.date.accessioned 2012-06-04T18:30:44Z
dc.date.available 2012-06-04T18:30:44Z
dc.date.issued 2011
dc.identifier.uri http://hdl.handle.net/10133/3081
dc.description ix, 67 leaves ; 29 cm en_US
dc.description.abstract The influence of play behavior on the brain was investigated through plasticity and metaplasticity methodology. Regions in both cortical and sub-cortical areas were investigated. Animals in both studies either experienced play with juvenile partners or did not experience play by being paired with an adult. Play experience alone was shown to affect the plasticity in the prefrontal cortex, although it did not show structural changes to sub-cortical regions. If animals were given nicotine after play experiences, the affects of play in the prefrontal cortex were abolished. In addition, playful behaviors appear to prime some sub-cortical regions of the brain for expression of later plasticity. Thus, play appears to alter the structure of multiple brain areas, but do so in different ways. en_US
dc.language.iso en_US en_US
dc.publisher Lethbridge, Alta. : University of Lethbridge, Dept. of Neuroscience, 2011 en_US
dc.relation.ispartofseries Thesis (University of Lethbridge. Faculty of Arts and Science) en_US
dc.subject Neuroplasticity en_US
dc.subject Neuroplasticity -- Research en_US
dc.subject Neuroplasticity -- Animal models en_US
dc.subject Rats as laboratory animals en_US
dc.subject Rats -- Behavior en_US
dc.subject Play behavior in animals en_US
dc.subject Play behavior in animals -- Research en_US
dc.subject Dissertations, Academic en_US
dc.title The effect of playful experiences on the plasticity and metaplasticity of the brain en_US
dc.type Thesis en_US
dc.publisher.faculty Arts and Science en_US
dc.publisher.department Department of Neuroscience en_US

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