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Escherichia coli O157:H7 lineage persistence and colonization of cattle in vitro

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dc.contributor.advisor Sharma, Ranjana
dc.contributor.advisor Selinger, Brent
dc.contributor.author Lowe, Ross M.S.
dc.contributor.author University of Lethbridge. Faculty of Arts and Science
dc.date.accessioned 2011-08-19T19:20:09Z
dc.date.available 2011-08-19T19:20:09Z
dc.date.issued 2009
dc.identifier.uri http://hdl.handle.net/10133/2509
dc.description xiii, 101 leaves ; 29 cm en_US
dc.description.abstract Escherichia coli O157:H7 is an important human pathogen that resides primarily in cattle and feedlot environments. E. coli O157:H7 can be divided into phylogenetic groups termed lineages; lineage I strains are responsible for most human illnesses. An understanding of the etiology of these lineages within cattle and the feedlot environment could allow for more effective surveillance and mitigation strategies. There were no lineage associated differences in growth or survival of E. coli O157:H7 in bovine feces at 4°C, 12°C or 25°C. Lineage I strains more readily colonized cattle jejunum tissue and a bovine colonic cell line than lineage II and intermediate type strains. Enhanced colonization of cattle by lineage I strains may increase the persistence of these strains in feedlots via re-infection and increased shedding. This outcome could increase the transmission of lineage I strains to the food supply and increase the potential for these strains to cause human illness. en_US
dc.language.iso en_US en_US
dc.publisher Lethbridge, Alta. : University of Lethbridge, Dept. of Biological Sciences, c2009 en_US
dc.relation.ispartofseries Thesis (University of Lethbridge. Faculty of Arts and Science) en_US
dc.subject Escherichia coli O157:H7 -- Research en_US
dc.subject Cattle -- Pathogens -- Research en_US
dc.subject Feedlots en_US
dc.subject Dissertations, Academic en_US
dc.title Escherichia coli O157:H7 lineage persistence and colonization of cattle in vitro en_US
dc.type Thesis en_US
dc.publisher.faculty Arts and Science en_US
dc.publisher.department Department of Biological Sciences en_US

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