Institutional Repository

Sex differences for object location memory in rats : the contribution of the dentate gyrus

DSpace/Manakin Repository

Show simple item record

dc.contributor.advisor Saucier, Deborah Ehresman, Crystal University of Lethbridge. Faculty of Arts and Science 2011-07-11T18:07:08Z 2011-07-11T18:07:08Z 2010
dc.description ix, 72 leaves : ill. ; 29 cm en_US
dc.description.abstract Females exhibit superior object location memory (OLM) compared to males, but the reasons for this sex difference remains unknown. This thesis investigates the role of the dentate gyrus (DG) in an OLM task in normal rats (Experiment 1) and after bilateral adrenalectomy (ADX; Experiment 2). ADX is known to reduce volume of the DG and impair spatial learning. There was no sex difference for OLM in Experiment 1 but females exhibited superior OLM in Experiment 2. Experiment 2 found a significantly smaller DG due to ADX but this had no effect on behaviour. The male DG was significantly larger than the female DG in both experiments. Behaviour during the OLM task was not a predictor of DG volume, although a larger than average DG was related to poor OLM memory in females Thus, the DG involvement for OLM appears to differ between the sexes. en_US
dc.language.iso en_US en_US
dc.publisher Lethbridge, Alta. : University of Lethbridge, Dept. of Neuroscience, c2010 en_US
dc.relation.ispartofseries Thesis (University of Lethbridge. Faculty of Arts and Science) en_US
dc.subject Memory en_US
dc.subject Dentate Gyrus -- Sex differences en_US
dc.subject Memory -- Testing en_US
dc.subject Rats as laboratory animals en_US
dc.subject Dissertations, Academic en_US
dc.title Sex differences for object location memory in rats : the contribution of the dentate gyrus en_US
dc.type Thesis en_US
dc.publisher.faculty Arts and Science en_US
dc.publisher.department Department of Neuroscience en_US Masters

Files in this item

This item appears in the following Collection(s)

Show simple item record

Search DSpace

Advanced Search


My Account