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The hippocampus, retrograde amnesia, and memory deconsolidation

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dc.contributor.advisor Sutherland, Robert
dc.contributor.author Epp, Jonathon
dc.contributor.author University of Lethbridge. Faculty of Arts and Science
dc.date.accessioned 2007-05-12T20:34:51Z
dc.date.available 2007-05-12T20:34:51Z
dc.date.issued 2005
dc.identifier.uri http://hdl.handle.net/10133/219
dc.description x, 78 leaves : ill. ; 29 cm. en
dc.description.abstract There are numerous clinical and experimental accounts of retrograde and anterograde amnesia resulting from damage to the hippocampus (HPC). Several theories on the HPC hold that only certain types of recent memories should be affected by HPC damage. These theories do not accurately predict the circumstances within which memories are vulnerable to HPC damage. Here I show the HPC plays a role in the formation and storage of a wider range of memories than is posited in contemporary theories. I will demonstrate that an important factor in elciting retrograde amnesia is the number of similar learning episodes. Exposure to multiple problems in the same task context leads to retorgrade amnesia that is not observed when only one problem is learned under otherwise identical parameters. When multiple discriminations are learned, the output of the HPC blocks recall from and future use of the extra-HPC memory system. en
dc.language.iso en_US en
dc.publisher Lethbridge, Alta. : University of Lethbridge, Faculty of Arts and Science, 2005 en
dc.relation.ispartofseries Thesis (University of Lethbridge. Faculty of Arts and Science) en
dc.subject Dissertations, Academic en
dc.subject Memory -- Physiological aspects en
dc.subject Memory -- Research en
dc.subject Rats as laboratory animals en
dc.subject Hippocampus (Brain) -- Physiology en
dc.subject Amnesia -- Research en
dc.subject Memory disorders en
dc.title The hippocampus, retrograde amnesia, and memory deconsolidation en
dc.type Thesis en
dc.publisher.faculty Arts and Science
dc.publisher.department Department of Neuroscience

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