Browsing University Archives by Subject "DNA repair -- Research"

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  • Wickersham, Stephanie (Lethbridge, Alta. : University of Lethbridge, Dept. of Biological Sciences, c2012Arts and ScienceDepartment of Biological Sciences, 2012)
    DNA double strand breaks (DSBs) are primarily repaired in eukaryotic cells by two different mechanisms – non-homologous end joining (NHEJ) or homologous recombination (HR). In mammalian somatic cells the balance between ...
  • Rutledge, Lesley R; University of Lethbridge. Faculty of Arts and Science (Lethbridge, Alta. : University of Lethbridge, Dept. of Chemistry and Biochemistry, c2011Arts and ScienceDepartment of Chemistry and Biochemistry, 2011)
    This thesis concentrates on understanding how individual nonspecific DNA–protein contacts are used in the excision mechanism of the human DNA repair enzyme, alkyladenine DNA glycosylase (AAG). Initially, studies focus ...

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