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  • Gharbawie, Omar A.; University of Lethbridge. Faculty of Arts and Science (Lethbridge, Alta. : University of Lethbridge, Faculty of Arts and Science, 2002Arts and ScienceDepartment of Neuroscience, 2002)
    The ascending cholinergic and serotonergic projections are central to cortical activation and normal behavior. The objective of this thesis was to determine whether unilaterally damaging both of these systems would disrupt ...
  • Hines, Dustin J.; University of Lethbridge. Faculty of Arts and Science (Lethbridge, Alta. : University of Lethbridge, Faculty of Arts and Science, 2004Faculty of Arts and ScienceDepartment of Neuroscience, 2004)
    The thesis examines the ability of animals to construct a home base. The home base is a point in space where animals rear, groom, and circle and is a primary element in organized spatial behaviour (Eilam and Golani 1989). ...
  • Filkowski, Jody; University of Lethbridge. Faculty of Arts and Science (Lethbridge, Alta. : University of Lethbridge, Dept. of Biological Sciences, 2010Arts and ScienceDepartment of Biological Sciences, 2010)
    Cytotoxic chemotherapy is extremely important in adjuvant treatment of breast cancer. Yet, tumours frequently acquire chemoresistance that correlates with increased aggressiveness and poor prognosis. Three theories exist ...
  • Baker, Mike; University of Lethbridge. Faculty of Arts and Science (Lethbridge, Alta. : University of Lethbridge, Faculty of Arts and Science, 2008Arts and ScienceDepartment of Biological Sciences, 2008)
    For over 100 years, cancer radiation therapy has provided patients with increased survival rates. Despite this success, radiation exposure poses a threat to the progeny of exposed parents. It causes transgenerational ...
  • Sidler, Corinne (Lethbridge, Alta. : University of Lethbridge, Dept. of Biological Sciences.Faculty of Arts and ScienceDepartment of Biological Sciences, 2014-10-03)
    Aging is associated with the functional decline of organs, and results in age-dependent differences in stress-sensitivity. Younger animals are more sensitive to mutagenic insults than adults, whereas in plants, the transition ...
  • Bilichak, Andriy (Lethbridge, Alta. : University of Lethbridge, Dept. of Biological SciencesArts and ScienceDepartment of Biological Sciences, 2013)
    Significant alterations in the environmental conditions can have pronounced effects on plant genome stability. Recent evidence argues for a global involvement of the components of epigenetic modules in the regulation of ...
  • Kutanzi, Kristy; University of Lethbridge. Faculty of Arts and Science (Lethbridge, Alta. : University of Lethbridge, Dept. of Biological Sciences, c2010Arts and ScienceDepartment of Biological Sciences, 2010)
    Epigenetics plays an important role in carcinogenesis with heritable changes in DNA methylation and histone modifications intricately linked to the initiation, promotion, and progression of cancer. Evidence shows that a ...
  • Bye, Cameron M.; University of Lethbridge. Faculty of Arts and Science (Lethbridge, Alta : University of Lethbridge, Dept. of NeuroscienceArts and ScienceDepartment of Neuroscience, 2017)
    The NMDA receptor is a proposed molecular mechanism responsible for the structural changes that occur in neurons during learning and memory formation. I investigate the role that NMDA receptors have in hippocampal spatial ...
  • Zhang, Xiaofei; University of Lethbridge. Faculty of Management (Lethbridge, Alta. : University of Lethbridge, Faculty of Management, c2012Management, 2012)
    This study examines the effects of changes in stock market microstructure on internal market efficiency and explores the relations among internal market efficiency, market co-movement and cross-market efficiency using ...
  • Holec, Victoria; University of Lethbridge. Faculty of Arts and Science (Lethbridge, Alta. : University of Lethbridge, [Dept. of] Neuroscience, c2013Arts and ScienceDepartment of Neuroscience, 2013)
    When given a choice between getting a high reward that requires climbing a high ramp or pressing a lever multiple times, versus freely obtaining a low reward, healthy rats prefer the former, while rats with lesions to ...
  • Gulbrandsen-MacDonald, Tine L; University of Lethbridge. Faculty of Arts and Science (Lethbridge, Alta. : University of Lethbridge, Dept. of Neuroscience, c2011Arts and ScienceDepartment of Neuroscience, 2011)
    Sutherland, Sparks and Lehmann (2010) proposed a new theory of memory consolidation, termed Distributed Reinstatement Theory (DRT), where the hippocampus (HPC) is needed for initial encoding but some types of memories are ...
  • Laskowski, Catherine (Lethbridge, Alta. : University of Lethbridge, Dept. of NeuroscienceArts and SciencesDepartment of Neuroscience, 2014)
    Damage to the medial prefrontal cortex (mPFC) often leads to problems characteristic of addiction, such as impulsivity and insensitivity to future consequences. To learn more about the role of this region, we studied the ...
  • Shams, Shirin; University of Lethbridge. Faculty of Management (Lethbridge, Alta. : University of Lethbridge, Faculty of ManagementManagement, 2015-06-29)
    In this study, we examine whether flexibility in stocks addition to and deletion from the S&P/TSX Composite Index enhanced its ability to act as a performance benchmark and represent the Canadian equity market. In May 2002, ...
  • Manossa, Geraldine; University of Lethbridge. Faculty of Arts and Science (Lethbridge, Alta. : University of Lethbridge, Faculty of Arts and Science, 2002Arts and ScienceDepartment of Native American Studies, 2002)
    This study examines the foundation of contemporary Cree performance, tracing its existence to traditional Cree narratives. Contained within traditional Cree stories is the trickster, Wasakaychak. These oral stories are ...
  • Hungerford, Lisa R.; University of Lethbridge. Faculty of Arts and Science (Lethbridge, Alta. : University of Lethbridge, Faculty of Arts and Science, 2007Faculty of Arts and ScienceDepartment of Geography, 2007)
    Building upon the ideas of decoupling and convergence, this thesis explores the structure of place-based community experience and levels of well-being for rural residents in southern Alberta. The research objectives are ...
  • Bailey, Gail (Lethbridge, Alta. : University of Lethbridge, Faculty of Education, c2013Education, 2013)
    Domestic abuse embodies many forms including physical, emotional, sexual, financial, and spiritual abuse (Statistics Canada, 2011a). This study explored the experience of rural Alberta women who have left domestic abuse, ...
  • Doberstein, William (Lethbridge, Alta. : University of Lethbridge, Dept. of HistoryArts and ScienceDepartment of History, 2014)
    The objective of this thesis is to fully deconstruct and isolate the considerable Samnite contributions to the Roman state during the period of the Samnite Wars. Although the literary sources have espoused a Samnitic origin ...
  • Meckelborg, Robert James; University of Lethbridge. Faculty of Arts and Science (Lethbridge, Alta. : University of Lethbridge, Faculty of Arts and Science, 2007Faculty of Arts and ScienceDepartment of English, 2007)
    Through an examination of Blake’s idea of Satan and his depiction of Satan and the rebel angels in the Paradise Lost design Satan Rousing his Legions, my thesis will demonstrate four principle findings, in addition to ...
  • Vandenberg, Shannon Y. (Lethbridge, Alta. : University of Lethbridge, Faculty of Health Sciences, c2013Health Sciences, 2013)
    The purpose of this grounded theory study was two-fold; first, to explore how mothers develop an understanding of childhood immunization which contributes to the decision¬making process resulting in a decision not to ...
  • Liu, Weiming; University of Lethbridge. Faculty of Arts and Science (Lethbridge, Alta. : University of Lethbridge, Faculty of Arts and Science, 2006Faculty of Arts and ScienceDepartment of Physics, 2006)
    Since 1982, the Si (111)-(7x7) surface has been extensively studied both theoretically and experimentally with the modern powerful tools of STM and Scanning Tunneling Spectroscopy (STS). In this work, a simple atomic orbital ...

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