The current competition will develop a sustainable pan-Canadian Research Core to coordinate research activities, facilitate sharing of expertise, knowledge and resources, to support the integration of sex- and gender-based analysis (SGBA) and ethical considerations in research related to the microbiome and human health, and to promote the translation of research outcomes into improved health, social, and economic benefits for Canadians, including both preventative and therapeutic interventions. The Research Core will also build on previous research investments by facilitating the addition of microbiome samples to existing large cohorts in Canada (e.g., Canadian Longitudinal Study on Aging (CLSA), Healthy Life Trajectories Initiative Linked International Intervention Cohorts (HeLTI LIIC), Canadian Partnership for Tomorrow Project (CPTP)). The Research Core will act as a resource to the Canadian Research community and to the Canadian Microbiome Initiative 2 Research Teams (to be funded in a future competition). The Research Teams will develop new knowledge on the causational roles of microbiome in human health with the goal of developing new preventative and therapeutic interventions. A series of workshops will facilitate interactions between the Research Core and Research Teams.
The objective of this funding opportunity is to develop a sustainable pan-Canadian Research Core that will:
- Support the sharing of cohort data, samples and bacterial strains to improve accessibility for Canadian researchers;
- Harmonize and optimize microbiome research protocols (11), including sample collection and processing in order to facilitate research reproducibility;
- Ensure that sex as a biological variable and gender as a social determinant of health are appropriately integrated into the data platform, research protocols and other core activities to expand the evidence base and research capacity in the field;
- Develop linkages among the Canadian research teams and linkages with international partners and stakeholders (e.g., the Joint Programme Initiative, Healthy Diet for a Healthy Life (JPI HDHL) Intestinal Microbiomics Initiative) in order to facilitate collaboration;
- Coordinate and facilitate multi-disciplinary training and mentoring to contribute to the development of the next generation of researchers; and
- Facilitate knowledge translation of Canadian microbiome research.
|Competition||201802IMR (Phase 1: Letter of Intent)||201808IMC (Phase 2: Full Application)|
|Anticipated Notice of Decision||2018-04-30||2018-11-29|
|Funding Start Date||2018-05-01||2018-11-01|