You will have to bring the response hub to your class and plug it into the computer you wish to use (laptop or classroom computer).
When you are ready to poll your students, launch the iClicker software and initiate the poll.
The iClicker interface hovers over any program, so you can ask the question via powerpoint, the web, or any other program you are using as an aid in your class.
When you start the poll using the iClicker software, your students will respond by selecting the appropriate response. All data is collected on the USB stick that plugs into the iClicker receiving hub.