Dr. Robert James Sutherland

Name: Robert James Sutherland

Phone: 403.394.3987

E-mail: robert.sutherland@uleth.ca

Office: EP1240

Lab: EP1205

Degrees:
PhD - Dalhousie University
MA - Dalhousie University
BSc - University of Toronto

Biography:

Rob Sutherland received his PhD in Psychology from Dalhousie University in Halifax, Nova Scotia. He moved to the Department of Psychology at University of Lethbridge in 1980, completing postdoctoral training in Neuropsychology on a NSERC Fellowship. From 1981 – 1991 he was a faculty member in Psychology and then from 1991 – 2001 he accepted a position at the University of New Mexico where he was Professor of Psychology, Physiology, & Neuroscience and Head of the Behavioural Neuroscience Area. He returned to Lethbridge where he is Professor of Psychology & Neuroscience, Alberta Heritage Medical Scientist, and Director of CCBN. His current research investigates the neurobiology of learning, memory, and amnesia in rodents and humans.

Recent
Publications:

Sutherland, RJ, Lehmann, H. (2011). Alternative conceptions of memory consolidation and the role of the hippocampus at the systems level in rodents. Current Opinion in Neurobiology, in press.

Faraji, J., Metz, G.A., Sutherland, R.J. (2011). Chronic stress prior to hippocampal stroke enhances post-stroke spatial deficits in the Ziggurat task. Neurobiology of Learning and Memory, 95, 335 – 345.

Spanswick, S.C., Lehmann, H., Sutherland, R.J. (2011). A novel animal model of hippocampal cognitive deficits, slow neurodegeneration, and neuroregeneration. Journal of Biomedicine and Biotechnology, Journal of Biomedicine and Biotechnology, in press, (accepted Jan 19, 2011).

Faraji J, Metz GA, Sutherland RJ (2011). Stress after hippocampal stroke enhances spatial performance in rats. Physiology & Behavior, 102, 389 – 399.

Epp, J.R., Spanswick, S.C., Sutherland, R.J. (2010). Time-course of hippocampal granule cell degeneration and changes in adult neurogenesis after adrenalectomy in rats. Neuroscience, revision submitted.

Lai, G-J., Spanswick, S., Lehmann, H., Yamazaki, H., Sutherland R.J. (2011). Behavior deficit and functional recovery after granule cell death in the hippocampus. submitted.

Spanswick, S.C., Lehmann, H., Sutherland, R.J. (2011). Does the Regeneration of Hippocampal Neurons Offer Hope for the Treatment of Cognitive Deficits? Regenerative Medicine, 6(1), 1 – 3.

McDonald, R.J., Yim, T.T., Lehmann, H., Sparks, F.T., Zelinski, E.L., Sutherland R.J., Hong, N.S. (2010). Expression of a conditioned place preference or spatial navigation task following muscimol-induced inactivations of the amygdala or dorsal hippocampus: A double dissociation in the retrograde direction. Brain Research Bulletin, 83, 29 - 37.

Spanswick, S.C., Sutherland, R.J. (2010). Object/Context Specific Memory Deficits Associated With Loss of Hippocampal Granule Cells After Adrenalectomy in Rats. Learning and Memory, 17(5), 241 - 245.

Faraji, J., Metz, G.A., Sutherland, R.J. (2010). Characterization of spatial performance in male and female Long-Evans rats by means of the Morris water task and the ziggurat task. Brain Research Bulletin, 81(1), 164 – 172.

Sutherland, R.J. (2010). Spatial Memory: A Rosetta Stone for Rat and Human Hippocampal Discourse: Theoretical Comment on GoodrichHunsaker and Hopkins. Behavioral Neuroscience, 124(3), 434 – 436.

Sutherland, R.J., Sparks, F.T., Lehmann, H. (2010). Hippocampus and Retrograde Amnesia in the Rat Model: A Modest Proposal for the Situation of Systems Consolidation. Neuropsychologia, 48(8), 2357 - 2369.

Travis, S.G., Fraser T. Sparks, F.T., Arnold, T., Lehmann, H., Sutherland, R.J., Whishaw, I.Q. (2010). Hippocampal damage produces retrograde but not anterograde amnesia for a cued location in a spontaneous exploratory task in rats. Hippocampus,
20(9), 1095 - 1104.

Lehmann, H., Sparks, F. T., O'Brien, J., McDonald, R. J., Sutherland, R. J. (2010). Retrograde amnesia for fear-potentiated startle in rats after complete, but not partial, hippocampal damage. Neuroscience, 167(4), 974 – 984.

Spanswick, S.C., Bray, D., Zelinski, E., Sutherland, R.J. (2009). A Novel Method for Reliable Nuclear Antibody Detection in Tissue with High Levels of Pathology-Induced Autofluorescence. Journal of Neuroscience Methods, 185(1), 45 - 49.

Melvin, N., Sutherland, R.J. (2010). Quantitative caveats of standard immunohistochemical procedures: Implications for optical disectorbased designs. Journal of Histochemistry & Cytochemistry, 58(7), 577 - 584.

Faraji, J., Metz, G., Sutherland, R. J. (2009). Stress and Corticosterone Enhance Cognitive Recovery from Hippocampal Stroke in Rats. Neuroscience Letters, 462, 248 - 252.

Lehmann, H., Sparks, F.T., Spanswick, S.C., Hadikin, C., McDonald, R.J., Sutherland, R.J. (2009). Making Context Memories Independent of the hippocampus. Learning and Memory, 16, 417 - 420.

Sutherland, R.J., O'Brien, J. (2009). The hippocampus and medial prefrontal cortex are necessary for episodic memory in the rat. Hippocampus, accepted for publication, 20 March 2009.

Driscoll, I., Hong, N.S., Craig, L.A., Sutherland, R.J., and McDonald, R.J. (2008). Enhanced cell death and learning deficits after a mini-stroke in aged hippocampus. Neurobiology of Aging, 29(12), 1847-1858.

Akers, KG; Johnson, TE; Rice, JP; Candelaria, FT; Weisend, MP; Sutherland,
RJ; Redhead, ES; Hamilton, DA. (2008). The relative influence of place
and direction in the Morris water task. Journal of Experimental
Psychology: Animal Behavior Processes, 34(1), 31-53.

Rudy, JW, Sutherland, RJ (2008). Is it Systems or Cellular
Consolidation? Time will tell. An Alternative interpretation of The Morris
Group's Recent Science Paper. Neurobiology of Learning and Memory,
89, 366 - 369

Whitlock, J., Sutherland, R.J., Witter, M.P., Moser, M-B., Moser, E.I. (2008). Navigating from hippocampus to parietal cortex. Proceedings of the National Academy of Science, 105(39), 14755 - 14762.

Tamminga, J; Koturbash, I; Baker, M; Kutanzi, K; Kathiria, P; Pogribny, IP; Sutherland, RJ; Kovalchuk, O. (2008). Paternal cranial irradiation induces distant bystander DNA damage in the germline and leads to epigenetic alterations in the offspring. Cell Cycle, 7, 1238 - 1245.

Sutherland, R.J., O'Brien, J., Lehmann, H. (2008). Absence of systems consolidation of fear memories after dorsal, ventral, or complete hippocampal damage. Hippocampus, 18, 710 - 718.

Epp, JR, Keith, JR, Spanswick, S, Stone, J, Prusky, GT, Sutherland, R.J. (2008). Retrograde amnesia for visual memories after hippocampal damage in rats. Learning and Memory, 15, 214-221.

Faraji, J., Lehmann, H., Metz, G., Sutherland, R.J. (2008). Rats with hippocampal lesions show impaired learning and memory in the ziggurat task: A new task to evaluate spatial behavior. Behavioural Brain Research, 189(1), 17 - 31.

Akers, KG; Johnson, TE; Rice, JP; Candelaria, FT; Weisend, MP; Sutherland, RJ; Redhead, ES; Hamilton, DA. (2008). The relative influence of place and direction in the Morris water task. Journal of Experimental Psychology: Animal Behavior Processes, 34(1), 31-53.

Hamilton, D. A., Akers, K. A., Johnson, T.E., Rice, J.T., Candelaria, F.T., Sutherland, R. J., Weisend, M.P. (2007). The relative influence of place and direction in the Morris water task. Journal of Experimental Psychology: Animal Behavior Processes, in press.

Rudy, JW, Sutherland, RJ (2007). Is it Systems or Cellular Consolidation? Time will tell. An Alternative interpretation of The Morris Group's Recent Science Paper. Neurobiology of Learning and Memory, in press, available on-line 30 Oct 2007.

Harch, PG, Kriedt, C, Van Meter, KW, Sutherland, RJ (2007). Hyperbaric oxygen therapy improves spatial learning and memory in a rat model of chronic traumatic brain injury. Brain Research, 1174, 120 - 129.

O'Brien, J. Sutherland, R.J. (2007). Evidence for episodic memory in a Pavlovian conditioning procedure in rats. Hippocampus, 17, 1149 - 1152.

Tata, MS, Mason, ALO, Sutherland, RJ (2007). Attention Modulates Responses to Motion Reversals in Human Visual Cortex. Neuroreport, 18(13), 1361 - 1365.

Keith, JR, Wu, Y, Epp, JR, Sutherland, RJ (2007). Fluoxetine and the Dentate Gyrus: Memory, Recovery of Function, and Electrophysiology. Behavioural Pharmacology, 18(5-6), 521 - 531.

Melvin, N. Poda, D., Sutherland, R.J. (2007). A simple and efficient alternative to implementing systematic random sampling in stereological designs without a Motorised Microscope Stage. Journal of Microscopy, 228(1), 103 - 106.

Driscoll, I., Hong, N.S., Craig, L.A., Sutherland, R.J., and McDonald, R.J. (2007). Enhanced cell death and learning deficits after a mini-stroke in aged hippocampus. Neurobiology of Aging, in press, available on-line 11 June 2007.

Lehmann, H., Lacanilao, S., and Sutherland, R. J. (2007). Complete or Partial Hippocampal Damage Produces Equivalent Retrograde Amnesia for Recent and Remote Contextual Fear Memories. European Journal of Neuroscience, 25(5), 1278 - 1286.

Melvin, N. R., Spanswick, S. C., Lehmann, H., and Sutherland. R. J. (2007). Differential Neurogenesis in the Adult Rat Dentate Gyrus: An identifiable zone that consistently lacks neurogenesis. European Journal of Neuroscience, 25 (4), 1023 - 1029.

Hamilton, D. A., Akers, K. A., Weisend, M.P., and Sutherland, R. J. (2007). How do room and apparatus cues control place navigation in the Morris water task?: Evidence for distinct contributions to a movement vector. Quarterly Journal of Experimental Psychology, 33(2), 100 - 114.

Spanswick, S., Epp, J.R., Keith, J.R., and Sutherland, R.J. (2007). Adrenalectomy-induced granule cell degeneration in the hippocampus causes spatial memory deficits that are not reversed by chronic treatment with corticosterone or fluoxetine. Hippocampus, 17, 137 - 146.

Sutherland, R.J., Lehmann, H., Spanswick, S.C., Sparks, F.T., Melvin, N.R. (2006). Growth points in research on memory and hippocampus. Canadian Journal of Experimental Psychology, 60(2), 166 - 180.

Wu, Y; Sutherland, RJ (2006). Hippocampal evoked potentials in novel environments: A behavioral clamping method. Behavioural Brain Research, 172, 63-71.

Thomson, L., and Sutherland, R.J. (2006). Interleukin-1ß induces anorexia but not spatial learning and memory deficits in the rat. Behavioural Brain Research, 170 (2), 302 - 307.

Bennett, B.M., Reynolds, J.N., Prusky, G.T., Douglas, R.M., Sutherland, R.J., and Thatcher, G.R.J. (2006). Cognitive deficits in rats after forebrain cholinergic depletion are reversed by a novel NO mimetic nitrate ester. Neuropsychopharmacology, 32(3), 505 - 513.

Driscoll, I., S.R. Howard, J.C. Stone, M.H. Monfils, B. Tomanek, W.M. Brooks, R.J. Sutherland (2006). The aging hippocampus: A multi-level analysis in the rat. Neuroscience, 139 (4), 1173 - 1185.

Hamilton, D.A., Prusky, G.T., Sutherland, R. J. (2006). The Morris water task and related methods. In Tasks and Techniques: A Sampling of Methodologies for the Investigation of Animal Learning, Behavior, and Cognition, M. Anderson (Ed.), Nova Science Publishers.